LUMIROUS support all women and couples who are trying to conceive
Type of Infertility
Infertility is classified into three category 1-Ovulation Disorder 2-Fertilization Disorder 3-Implantation disorder
Ovulation Disorder Infertility caused because the eggs don’t grow due to the lack of secretion of female hormones.
Endocrine and Ovulation Factor The secretion of gonadotropin controlling the period cycle is adjusted by gonadotropin secreted from the part in the brain called hypothalamus.
In other words, a series of hormone secretions such as hypothalamic-> pituitary-> ovary takes periodic ovulation.
If there is an abonormality in these hormone secretion, ovulation disorder occurs and can be cause of infertility.
If women have irregular period,there is a possbility that women have ovulation disorder.
Hormone secretion is subject to infertility because it can affect to mental stress, obesity and weight loss by rapid pace. Polycystic ovary syndrome (PCOS) is the inability to ovulate due to the failure of follicles to mature.
It occurs in 6-10% of women of reproductive age and is the most common cause of ovulation problems.
Infertility due to premature ovarian failure, which occurs when the ovarian function is extremely low in the 20s or 30s, is also rare.
Fllapion Tube Factors The most common cause (30-40%) is infertility due to fallopian tube factors, with more than 60% of infertility caused by narrowing or blockage of the fallopian tubes due to chlamydial infection and adhesions around the fallopian tubes.
Narrowing of the fallopian tubes and adhesions around the fallopian tubes make it difficult for the ovulated egg to be taken in by the fallopian tubes or to travel to the uterus, resulting in infertility.
Women with chlamydia are often feel no symptoms which makes it difficult to recognize the infection.
Other causes of infertility include adhesions around the fallopian tubes due to pelvic surgery such as appendicitis or endometriosis.
Cervical factor In order for a pregnancy to occur, a sperm must pass through the cervix to reach the egg, but if the condition of the cervix and cervical mucus are not suitable for the passage of sperm, it makes difficult to conceive.
Cervical factors include inadequate cervical mucus production (low cervical mucus volume and increased viscosity), cervicitis, cervical polyps, and cervical stenosis.
Inadequate cervical mucus production may be related to endocrine abnormalities such as insufficient estrogen action.
Male Factors The causes of male infertility include sexual dysfunction that results in poor ejaculation, spermatogenesis dysfunction, impaired sperm passage, and inflammation of the internal genitalia.
The most common of these is spermatogenesis dysfunction, which is the inability to produce enough sperm, and accounts for 80-90% of all cases.
A semen analysis will be performed to check the characteristics, volume, concentration, and motility of the semen, and the best treatment method will be discussed.
Immune factors Fertilization problems occur due to the production of antibodies (antisperm antibodies) that damage sperm due to immune abnormalities. Antisperm antibodies can be possessed by men or women.
When a man possesses antisperm antibodies, the presence of the antibodies in his semen will impair the motility of his sperm as soon as they are ejaculated.
On the other hand, if the woman has antisperm antibodies, the secretion of antibodies into the uterine lumen and cervical mucus prevents sperm from entering the uterus, and the antibodies also prevent fertilization itself.
Uterine Factors Abnormalities in the uterus can prevent the implantation of a fertilized egg, resulting in infertility.
Uterine abnormalities include uterine fibroids, endometriosis, uterine malformations, and Ascherman’s syndrome.
Uterine fibroids, especially submucosal fibroids that rise to the inside of the uterus, not only cause implantation problems for fertilized eggs, but also prevent sperm from reaching the egg, making it difficult to conceive.
Similarly, endometrial polyps can also be a cause of infertility.
Endometriosis is known to cause infertility when the endometrium, which is only supposed to be inside the uterus, repeatedly multiplies outside the uterus (in the ovaries, peritoneum, etc.) causing pain and inflammation.
Uterine malformation is a congenital deformity of the uterus. A septate uterus, in which a wall called a septum remains in the uterus during the formation process, is said to be the most prone to infertility.
Asherman’s syndrome is a condition in which the uterine lumen has become adherent and blocked, and is caused by trauma such as intrauterine curettage or manipulation during childbirth.